Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 20/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 16/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.49 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011566 | 1.00 | SLC16A1 (0.68) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7005614 | 0.89 | SLC16A1 (0.52) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7991784 | 0.84 | SLC16A1 (0.47) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| Lithium SCHEMBL7977772 | 0.84 | SLC16A1 (0.47) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7977767 | 0.84 | SLC16A1 (0.47) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7007756 | 0.83 | SLC16A1 (0.46) | SLC16A1CYP2C9CYP3A4 | |
| Lithium Ion SCHEMBL7977769 | 0.82 | SLC16A1 (0.45) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL7011954 | 0.76 | SLC16A1 (0.43) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7004038 | 0.75 | SLC16A1 (0.42) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| Lithium SCHEMBL7004046 | 0.75 | SLC16A1 (0.42) | SLC16A1CYP2C9CYP3A4SLC16A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107973-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012514-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-09 | — | — | WO | disclosed |