Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419226 | 0.95 | HTT (0.47) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL31545402 | 0.81 | TYR (0.50) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL10404681 | 0.81 | HSP90AB1 (0.47) | HTTKDM4ETYRTSHRHSP90AB1 | |
| SCHEMBL31544881 | 0.80 | TYR (0.53) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL70058 | 0.79 | TYR (0.51) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL22068259 | 0.79 | TYR (0.47) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL7772658 | 0.79 | CNR2 (0.38) | HTTTYRMEN1MAPTKMT2A | |
| SCHEMBL5274961 | 0.78 | HTT (0.44) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL8824081 | 0.77 | NAAA (0.46) | HTTKDM4ETYRMEN1TP53 | |
| SCHEMBL3836152 | 0.77 | NAAA (0.46) | HTTKDM4ETYRMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496640-B2 | I-ray sensitive positive resist composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 2001-09-19 | — | — | EP | disclosed |
| EP-0496640-B1 | I-ray sensitive positive resist composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5413896-A | Light sensitive element with novolak resin and quinonediazide compounds | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0496640-A1 | I-ray sensitive positive resist composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |