SCHEMBL70058

SCHEMBL70058

CCCCCCC(C)c1ccc(O)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 5/20 0.51
HTT P42858 2/20 0.51
TP53 P04637 2/20 0.51
CYP3A4 P08684 2/20 0.51
MEN1 O00255 1/20 0.51
ALOX5 P09917 1/20 0.51
MAPT P10636 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
KDM4E B2RXH2 2/20 0.42
GPR84 Q9NQS5 1/20 0.41
SRC P12931 1/20 0.41
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL469144 0.93 TYR (0.49) TYRHTTTP53CYP3A4MEN1
SCHEMBL11804812 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL4354699 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL10600531 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL11647604 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL7552547 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL8639228 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL11095669 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL419569 0.87 TYR (0.47) TYRHTTTP53CYP3A4MEN1
SCHEMBL71452 0.86 TYR (0.49) TYRHTTTP53CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11090863-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2021-08-17 US disclosed
US-20200171742-A1 METHODS OF MANUFACTURING ARTICLES UTILIZING FOAM PARTICLES NIKE, INC. 2020-06-04 US disclosed
WO-2018134427-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-07-26 WO disclosed
US-8318217-B2 Compositions comprising an anti-inflammatory blend JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-11-27 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-20120128605-A1 COMPOSITIONS COMPRISING A SKIN-LIGHTENING RESORCINOL AND A SKIN DARKENING AGENT JOHNSON & JOHNSON CONSUMER INC. 2012-05-24 US disclosed
US-20120128613-A1 COMPOSITIONS COMPRISING A SKIN-LIGHTENING RESORCINOL AND A SKIN DARKENING AGENT NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR 2012-05-24 US disclosed
US-20120101156-A1 COMPOSITIONS COMPRISING A RETINOID AND AN NFkB-INHIBITOR AND THEIR METHODS OF USE KENVUE BRANDS LLC 2012-04-26 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-8075930-B2 Extracts of Phyllanthus niruri JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2011-12-13 US disclosed
US-8075931-B2 Extracts of Phyllanthus niruri JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2011-12-13 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20110081431-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A NON-RETINOID COLLAGEN PROMOTER KENVUE BRANDS LLC 2011-04-07 US disclosed
US-20110081305-A1 COMPOSITIONS COMPRISING A SKIN-LIGHTENING RESORCINOL AND A SKIN DARKENING AGENT JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2011-04-07 US disclosed
US-20110081433-A1 COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND JOHNSON & JOHNSON CONSUMER INC. 2011-04-07 US disclosed
US-20110081432-A1 EXTRACTS OF PHYLLANTHUS NIRURI JOHNSON & JOHNSON CONSUMER INC. 2011-04-07 US disclosed
US-20110081308-A1 EXTRACTS OF PHYLLANTHUS NIRURI JOHNSON & JOHNSON CONSUMER INC. 2011-04-07 US disclosed
US-20110081430-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2011-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110081431-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A NON-RETINOID COLLAGEN PROMOTER NFKBIA, NFRKB, NFKB1 TYR 4184/4885HTT 3686/4885TP53 244/4885
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TYR 134/4885HTT 1871/4885TP53 1492/4885
US-20120128605-A1 COMPOSITIONS COMPRISING A SKIN-LIGHTENING RESORCINOL AND A SKIN DARKENING AGENT CUTA, NQO1, RBP4 TYR 5/4885HTT 1074/4885TP53 3191/4885
US-20120101156-A1 COMPOSITIONS COMPRISING A RETINOID AND AN NFkB-INHIBITOR AND THEIR METHODS OF USE NFKBIA, NFKB2, NFKB1 TYR 1074/4885HTT 3568/4885TP53 650/4885
US-20110081430-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER NFKBIA, NFKB1, NFKB2 TYR 199/4885HTT 620/4885TP53 189/4885
US-20110081308-A1 EXTRACTS OF PHYLLANTHUS NIRURI CUTA, COLGALT1, COL1A1 TYR 224/4885HTT 2143/4885TP53 3940/4885
US-20110081433-A1 COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND NFKBIA, NFKB2, NFKB1 TYR 2278/4885HTT 1636/4885TP53 1865/4885
US-20120128613-A1 COMPOSITIONS COMPRISING A SKIN-LIGHTENING RESORCINOL AND A SKIN DARKENING AGENT CUTA, NQO1, RBP4 TYR 5/4885HTT 1074/4885TP53 3191/4885
US-20110081432-A1 EXTRACTS OF PHYLLANTHUS NIRURI CUTA, COLGALT1, COL1A1 TYR 224/4885HTT 2143/4885TP53 3940/4885
US-20110081305-A1 COMPOSITIONS COMPRISING A SKIN-LIGHTENING RESORCINOL AND A SKIN DARKENING AGENT CUTA, NQO1, RBP4 TYR 5/4885HTT 1074/4885TP53 3191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.