Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661345 | 0.89 | PNMT (0.49) | MAPTMEN1TP53KMT2AKDM4E | |
| SCHEMBL7659438 | 0.82 | GFER (0.61) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7664966 | 0.82 | MAPT (0.61) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7665040 | 0.82 | MAPT (0.56) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7657390 | 0.82 | MAPT (0.56) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7654276 | 0.82 | MAPT (0.58) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7858184 | 0.81 | MAPT (0.54) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7659815 | 0.81 | PKM (0.48) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7656710 | 0.80 | MAPT (0.56) | MAPTHTTRAB9AMEN1TP53 | |
| SCHEMBL7658164 | 0.80 | MAPT (0.53) | MAPTHTTRAB9AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | disclosed |