Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292487 | 0.91 | DNM1 (0.35) | MAPTDNM1TSHRALDH1A1FDPS | |
| SCHEMBL1961199 | 0.84 | MAPT (0.43) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL27453782 | 0.81 | MAPT (0.45) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL27855630 | 0.81 | MAPT (0.45) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL1697637 | 0.81 | MAPT (0.45) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL27974305 | 0.81 | MAPT (0.45) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL7688271 | 0.81 | MAPT (0.45) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL30892684 | 0.81 | MAPT (0.45) | MAPTLMNADNM1TSHRTHRB | |
| SCHEMBL1245652 | 0.80 | — | — | |
| SCHEMBL10394693 | 0.79 | MAPT (0.37) | MAPTLMNADNM1TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791069-A1 | MICROBIAL TRANSFORMATION PROCESS FOR OBTAINING ANTIBIOTIC GE 2270 FACTOR D 2? | Biosearch Italia S.p.A. (IT) | 1997-08-27 | — | — | EP | claimed |
| WO-1996014427-A1 | MICROBIAL TRANSFORMATION PROCESS FOR OBTAINING ANTIBIOTIC GE 2270 FACTOR D¿2? | GRUPPO LEPETIT S.P.A. (IT) | 1996-05-17 | — | — | WO | claimed |
| EP-0700399-B1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | LEPETIT SPA (IT) | 2001-10-04 | — | — | EP | disclosed |
| EP-0751940-B1 | SESQUITERPENIC DERIVATIVES | LEPETIT SPA (IT) | 1999-05-12 | — | — | EP | disclosed |
| US-5854036-A | Sesquiteterpenic dervatives | GRUPPO LEPETIT S.P.A. (IT) | 1998-12-29 | — | — | US | disclosed |
| US-5843890-A | Antibiotic GE 2270 factors B1, B2, C1, C2, D1, D2, E and T | GRUPPO LEPETIT S.P.A. (IT) | 1998-12-01 | — | — | US | disclosed |
| US-5786350-A | CONDENSATION; HYDROLYSIS; DEPROTECTING | GRUPPO LEPETIT S.P.A. (IT) | 1998-07-28 | — | — | US | disclosed |
| US-5747295-A | Antibiotic GE 2270 factors B1, B2, C1, C2, D1, D2, E and T | GRUPPO LEPETIT S.P.A. (IT) | 1998-05-05 | — | — | US | disclosed |
| EP-0529410-B1 | Antibiotic GE 2270 factor C2a | BIOSEARCH ITALIA SPA (IT) | 1998-02-25 | — | — | EP | disclosed |
| EP-0675900-B1 | ANTIBIOTICS GE 37468 A, B AND C | BIOSEARCH ITALIA SPA (IT) | 1998-02-18 | — | — | EP | disclosed |
| US-5618724-A | Antibiotics GE 37468 A, B and C | GRUPPO LEPETIT SPA (IT) | 1997-04-08 | — | — | US | disclosed |
| WO-1994028002-A1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1994-12-08 | — | — | WO | disclosed |
| WO-1994014838-A1 | ANTIBIOTICS GE 37468 A, B AND C | GRUPPO LEPETIT S.P.A. (IT) | 1994-07-07 | — | — | WO | disclosed |
| US-5322777-A | Administering for bacterial infections; obtained from culture of Planobispora rosea ATCC 53773 | GRUPPO LEPETIT S.P.A. (IT) | 1994-06-21 | — | — | US | disclosed |
| EP-0359062-B1 | Antibiotic GE 2270 | LEPETIT SPA (IT) | 1994-02-16 | — | — | EP | disclosed |
| WO-1993013217-A1 | ANTIBIOTIC GE 21640A | GRUPPO LEPETIT S.P.A. (IT) | 1993-07-08 | — | — | WO | disclosed |
| US-5202241-A | Spectrum analysis of physiochemical and biological properties; useful in treatment of infection diseases involving microorganism susceptible to them; culture product | GRUPPO LEPETIT S.P.A. (IT) | 1993-04-13 | — | — | US | disclosed |
| EP-0529410-A2 | Antibiotic GE 2270 factor C2a | GRUPPO LEPETIT S.p.A. (IT) | 1993-03-03 | — | — | EP | disclosed |
| EP-0451486-A1 | Antibiotic GE 2270 factors B1, B2, C1, C2, D1, D2,E and T | GRUPPO LEPETIT S.p.A. (IT) | 1991-10-16 | — | — | EP | disclosed |
| EP-0359062-A2 | Antibiotic GE 2270 | GRUPPO LEPETIT S.p.A. (IT) | 1990-03-21 | — | — | EP | disclosed |