SCHEMBL10394693

SCHEMBL10394693

CCCCCCC(F)C(F)(F)C(F)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
FDPS P14324 5/20 0.34
LMNA P02545 1/20 0.33
LPAR1 Q92633 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
LAP3 P28838 1/20 0.32
DNM1 Q05193 2/20 0.32
SMPD1 P17405 3/20 0.32
OPRM1 P35372 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27552948 0.79 MAPT (0.42) MAPTFDPSLMNADNM1OPRM1
SCHEMBL45230 0.79 MAPT (0.42) MAPTFDPSLMNADNM1OPRM1
SCHEMBL7856017 0.79 MAPT (0.42) MAPTFDPSLMNADNM1OPRM1
SCHEMBL45436 0.77 MAPT (0.39) MAPTFDPSLMNADNM1OPRM1
SCHEMBL1961199 0.77 MAPT (0.43) MAPTFDPSLMNADNM1OPRM1
SCHEMBL23825039 0.76 MAPT (0.44) MAPTFDPSLMNA
SCHEMBL23825142 0.76 MAPT (0.44) MAPTFDPSLMNA
SCHEMBL23825196 0.76 MAPT (0.44) MAPTFDPSLMNA
SCHEMBL621864 0.76 MAPT (0.39) MAPTFDPSLMNADNM1OPRM1
SCHEMBL23824979 0.76 MAPT (0.44) MAPTFDPSLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4910041-A Generated arced plasma; applying a magnetic field JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-03-20 US disclosed
US-4693799-A LOW TEMPERATURE PULSE DISCHARGING JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-09-15 US disclosed