Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808215 | 0.82 | LMNA (0.67) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL97532 | 0.82 | DRD2 (0.55) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL2000837 | 0.79 | LMNA (0.59) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL31267597 | 0.77 | DRD2 (0.54) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL9808100 | 0.77 | DRD2 (0.72) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL1685432 | 0.77 | DRD2 (0.62) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL3957187 | 0.77 | LMNA (0.61) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL11519069 | 0.77 | DRD4 (0.44) | SMN1; SMN2DRD2DRD4KCNH2HRH3 | |
| SCHEMBL4993415 | 0.77 | KCNA3 (0.58) | DRD2DRD4 | |
| SCHEMBL2096611 | 0.76 | KMT2A (0.62) | LMNAMAPK1HTTSMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660716-B1 | NON-ACIDIC CYCLOPENTANE HEPTANOIC ACID, 2-CYCLOALKYL OR ARYLALKYL DERIVATIVES AS THERAPEUTIC AGENTS | ALLERGAN INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-5607978-A | PROSTAGLANDINS FOR VISION DEFECTS | ALLERGAN (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0660716-A1 | NON-ACIDIC CYCLOPENTANE HEPTANOIC ACID, 2-CYCLOALKYL OR ARYLALKYL DERIVATIVES AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5352708-A | For treating glaucoma | ALLERGAN, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| US-RE29926-E | 2-Decarboxy-2-hydroxy-methyl-16-fluoro-PGE1 compounds | THE UPJOHN COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4122282-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4107191-A | PROSTAGLANDINS, BLOOD PRESSURE LOWERING, LABOR INDUCTION, REPRODUCTIVE-CYCLE REGULATION, GASTRIC ANTISECRETORY | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4104474-A | PROSTAGLANDINS, HYPOTENSIVE, OXYTOCICS, ANTIFERTILITY, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4099015-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4058564-A | PROSTAGLANDINS; HYPOTENSIVE, LABOR INDUCERS, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1977-11-15 | — | — | US | disclosed |
| US-4055602-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4028419-A | PROSTAGLANDINS | THE UPJOIN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |