Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854247 | 0.81 | POLB (0.47) | POLBMAPTPTPN1LMNAGAA | |
| SCHEMBL7854346 | 0.77 | POLB (0.50) | POLBMAPTLMNAGAAGLA | |
| SCHEMBL7855687 | 0.76 | POLB (0.52) | POLBMAPTLMNAGAAGLA | |
| SCHEMBL7854007 | 0.70 | PTPN1 (0.45) | POLBMAPTPTPN1LMNAHTT | |
| SCHEMBL11696347 | 0.69 | POLB (0.68) | POLBMAPTLMNAGAANPC1 | |
| SCHEMBL12444397 | 0.69 | POLB (1.00) | POLBMAPTLMNAGAAGLA | |
| SCHEMBL7856785 | 0.68 | TP53 (0.43) | POLBMAPTLMNAGLAMGLL | |
| SCHEMBL335296 | 0.67 | GABRA1 (0.59) | POLBMAPTPTPN1GAA | |
| SCHEMBL2843664 | 0.67 | PTPN1 (0.54) | POLBPTPN1NPC1RAB9A | |
| SCHEMBL7854244 | 0.67 | MAPT (0.41) | MAPTGAAHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |