Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192073 | 0.87 | KMT2A (0.55) | KMT2AALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL1644599 | 0.85 | ALDH1A1 (0.58) | KMT2AALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL7341366 | 0.85 | KMT2A (0.54) | KMT2AALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL10786974 | 0.82 | MAPT (0.43) | KMT2AALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL2354936 | 0.79 | ALDH1A1 (0.62) | KMT2AALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL6398309 | 0.79 | KMT2A (0.71) | KMT2AALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL11107197 | 0.79 | CES2 (0.52) | ALDH1A1TDP1SMN1; SMN2POLBRAB9A | |
| SCHEMBL28203029 | 0.79 | KMT2A (0.47) | KMT2AALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL8683857 | 0.79 | KMT2A (0.47) | KMT2AALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL1094136 | 0.78 | KMT2A (0.65) | KMT2AALDH1A1CYP3A4TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003939-B | Diaryl substitution thiohydantoin class compound and preparation method and application | 山东大学 | 2017-07-07 | — | — | CN | disclosed |
| EP-0819113-B1 | BENZAMIDES FOR NEURODEGENERATIVE DISORDER TREATMENT | CENTAUR PHARMACEUTICALS INC (US) | 2001-06-27 | — | — | EP | disclosed |