Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 16/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866842 | 0.89 | SLC6A4 (0.42) | BRS3CAPN1 | |
| SCHEMBL7668198 | 0.81 | BCL2L1 (0.38) | BRS3BCL2L1BAD | |
| SCHEMBL7668202 | 0.81 | BCL2L1 (0.38) | BRS3BCL2L1BAD | |
| SCHEMBL7668328 | 0.77 | BCL2L1 (0.38) | BRS3BCL2L1BAD | |
| SCHEMBL7668332 | 0.77 | BCL2L1 (0.38) | BRS3BCL2L1BAD | |
| SCHEMBL7674885 | 0.76 | NAMPT (0.39) | BRS3BCL2L1BAD | |
| SCHEMBL7667000 | 0.76 | NAMPT (0.39) | BRS3BCL2L1BADCAPN1 | |
| SCHEMBL7667006 | 0.76 | NAMPT (0.39) | BRS3BCL2L1BADCAPN1 | |
| SCHEMBL7674887 | 0.76 | NAMPT (0.39) | BRS3BCL2L1BAD | |
| SCHEMBL8185614 | 0.74 | BRS3 (0.43) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140858-A2 | ARYLPROPENYLIMIDAZOLES AS FARNESYL-PROTEIN TRANSFERASE INHIBITORS | AstraZeneca AB (SE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039716-A2 | ARYLPROPENYLIMIDAZOLES AS FARNESYL-PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA AB (SE) | 2000-07-06 | — | — | WO | disclosed |