Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084481 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL3311524 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL14690904 | 0.78 | USP2 (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL12892832 | 0.77 | USP2 (0.60) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL10085039 | 0.76 | PARG (0.58) | ALDH1A1KDM4EGAAHSD17B10KMT2A | |
| SCHEMBL10086065 | 0.75 | KDM4E (0.67) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL9049869 | 0.74 | CA12 (0.60) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10084475 | 0.74 | HSD17B10 (0.47) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL10085092 | 0.74 | POLB (0.43) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL10085091 | 0.74 | POLB (0.48) | ALDH1A1KDM4EGAAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001004103-A1 | BENZAZEPINONES AND QUINAZOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-01-18 | — | — | WO | disclosed |