Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1130886 | 0.97 | POLB (0.33) | POLBGPR3 | |
| Bromide SCHEMBL7205887 | 0.97 | POLB (0.33) | POLBGPR3 | |
| SCHEMBL4577361 | 0.97 | POLB (0.33) | POLBGPR3 | |
| Hydrochloric Acid SCHEMBL6553975 | 0.90 | PPIA (0.35) | — | |
| Hydrochloric Acid SCHEMBL6555613 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7717009 | 0.87 | GAA (0.35) | GPR3 | |
| Hydrochloric Acid SCHEMBL7719195 | 0.87 | PDK2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1135091 | 0.86 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL1135043 | 0.86 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL1135042 | 0.86 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180244812-A1 | Spherical Supported Transition Metal Catalyst | PETROCHINA COMPANY LIMITED (CN) | 2018-08-30 | — | — | US | claimed |
| US-9115229-B2 | Particulate metallocene-alumoxane catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2015-08-25 | — | — | US | claimed |
| US-20140213743-A1 | Particulate Metallocene-Alumoxane Catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-07-31 | — | — | US | claimed |
| US-8722567-B2 | Particulate metallocene-alumoxane catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-05-13 | — | — | US | claimed |
| US-20140045681-A1 | Particulate Metallocene-Alumoxane Catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-02-13 | — | — | US | claimed |
| US-20130225707-A1 | Articles Formed From Polypropylene Prepared with a Single-Site Catalyst and Poly(hydroxyl carboxylic acid) Blends | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-08-29 | — | — | US | claimed |
| US-8445595-B2 | Polypropylene prepared with a single-site catalyst and poly(hydroxyl carboxylic acid) blends | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-05-21 | — | — | US | claimed |
| EP-2160233-B1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | TOTAL RES & TECHNOLOGY FELUY (BE) | 2012-10-17 | — | — | EP | claimed |
| US-20100234544-A1 | Process for the Polymerisation of Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-09-16 | — | — | US | claimed |
| US-7662895-B2 | comprising polypropylene which is produced in presence of a metallocene transition metal catalyst and an activator; peak melting point temperature below about 110 degrees C., a tensile set of 40% or less, and greater than or equal to about 60% [r]dyads | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-5696045-A | USING MIXTURE OF ZIRCONOCENE CATALYSTS | TARGOR GMBH (DE) | 1997-12-09 | — | — | US | claimed |
| US-5652315-A | Method for preparing ethylene copolymer | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-07-29 | — | — | US | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | claimed |
| US-5587501-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-24 | — | — | US | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| US-5539066-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | claimed |
| EP-0516018-B1 | Process for preparing olefin polymers with large molecular weight distribution | HOECHST AG (DE) | 1996-03-27 | — | — | EP | claimed |
| EP-0516019-B1 | Process for preparing syndiotactic polyolefins with large molecular weight distribution | HOECHST AG (DE) | 1995-12-27 | — | — | EP | claimed |
| EP-0572990-A2 | Method for preparing ethylene copolymer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-08 | — | — | EP | claimed |