Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16594091 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL78567 | 0.90 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL6553917 | 0.87 | PPIA (0.33) | PPIAMEN1LMNAKMT2A | |
| Fluoride Ion SCHEMBL1130886 | 0.87 | POLB (0.33) | — | |
| SCHEMBL4577361 | 0.87 | POLB (0.33) | — | |
| Bromide SCHEMBL7205887 | 0.87 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL7711393 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL6553416 | 0.83 | PPIA (0.32) | PPIA | |
| Hydrochloric Acid SCHEMBL6555613 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL5084117 | 0.82 | LMNA (0.34) | MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |