SCHEMBL785685

SCHEMBL785685

Cc1cc(C)c(N2C(=O)c3ccc(C(c4ccc5c(c4)C(=O)N(c4c(C)cc(C)c(N6C(=O)c7ccc(C(c8ccc9c(c8)C(=O)N(c8c(C)cc(C)c(N%10C(=O)c%11ccc(C(c%12ccc%13c(c%12)C(=O)NC%13=O)(C(F)(F)F)C(F)(F)F)cc%11C%10=O)c8C)C9=O)(C(F)(F)F)C(F)(F)F)cc7C6=O)c4C)C5=O)(C(F)(F)F)C(F)(F)F)cc3C2=O)c(C)c1C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.34
DPP4 P27487 2/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP2 O95551 2/20 0.32
CA9 Q16790 3/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
POLB P06746 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18136214 0.99 ANPEP (0.34) ANPEPDPP4MEN1KMT2AKDM4E
SCHEMBL26077297 0.96 TDP2 (0.34) ANPEPDPP4TDP2
SCHEMBL12691343 0.92 ANPEP (0.36) ANPEPDPP4MEN1KMT2AKDM4E
SCHEMBL819167 0.90 ANPEP (0.33) ANPEPDPP4MEN1KMT2AKDM4E
SCHEMBL18068730 0.90 ANPEP (0.33) ANPEPDPP4MEN1KMT2AKDM4E
SCHEMBL15493904 0.89 ANPEP (0.36) ANPEPDPP4MEN1KMT2AHSD17B10
SCHEMBL20835100 0.88 CA9 (0.34) ANPEPDPP4MEN1KMT2AKDM4E
SCHEMBL25688434 0.87 ANPEP (0.39) ANPEPDPP4MEN1KMT2AKDM4E
SCHEMBL26490051 0.87 ANPEP (0.32) ANPEPDPP4
SCHEMBL822115 0.86 ANPEP (0.33) ANPEPDPP4MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9718031-B2 Composite hollow fiber membranes useful for CO2 removal from natural gas CHEVRON U.S.A. INC. (US) 2017-08-01 US disclosed
US-20150011815-A1 COMPOSITE HOLLOW FIBER MEMBRANES USEFUL FOR CO2 REMOVAL FROM NATURAL GAS GEORGIA TECH RESEARCH CORPORATION (US) 2015-01-08 US disclosed
US-8449651-B2 Methods of preparing a crosslinked fiber membrane CHEVRON U.S.A. INC. (US) 2013-05-28 US disclosed
US-8328906-B2 Method of making a crosslinked fiber membrane from a high molecular weight, monoesterified polyimide polymer CHEVRON U.S.A. INC. (US) 2012-12-11 US disclosed
US-20120067208-A1 METHOD OF MAKING A CROSSLINKED FIBER MEMBRANE FROM A HIGH MOLECULAR WEIGHT, MONOESTERIFIED POLYIMIDE POLYMER GEORGIA TECH RESEARCH CORPORATION (US) 2012-03-22 US disclosed
US-20120048107-A1 METHODS OF PREPARING A CROSSLINKED FIBER MEMBRANE CHEVRON U.S.A. INC. 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011815-A1 COMPOSITE HOLLOW FIBER MEMBRANES USEFUL FOR CO2 REMOVAL FROM NATURAL GAS C9, HRH3, C5 ANPEP 4033/4885DPP4 4069/4885MEN1 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.