SCHEMBL822115

SCHEMBL822115

Cc1cc(C)c(N2C(=O)c3ccc(-c4ccc5c(c4)C(=O)N(c4c(C)cc(C)c(N6C(=O)c7ccc(C(c8ccc9c(c8)C(=O)N(C)C9=O)(C(F)(F)F)C(F)(F)F)cc7C6=O)c4C)C5=O)cc3C2=O)c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.33
DPP4 P27487 2/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
APP P05067 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA9 Q16790 2/20 0.31
ALOX15 P16050 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15493904 0.94 ANPEP (0.36) ANPEPDPP4NR1H2NR1H3ALDH1A1
SCHEMBL17878031 0.91 ANPEP (0.33) ANPEPDPP4NR1H2NR1H3ALDH1A1
SCHEMBL26077297 0.91 TDP2 (0.34) ANPEPDPP4
SCHEMBL26489721 0.90 ANPEP (0.33) ANPEPDPP4NR1H2NR1H3ALDH1A1
SCHEMBL16521141 0.90 ANPEP (0.33) ANPEPDPP4NR1H2NR1H3ALDH1A1
SCHEMBL26490000 0.88
SCHEMBL20886666 0.87 ANPEP (0.38) ANPEPDPP4NR1H2NR1H3ALDH1A1
SCHEMBL15448504 0.86 ANPEP (0.42) ANPEPDPP4ALDH1A1MEN1MAPT
SCHEMBL785685 0.86 ANPEP (0.34) ANPEPDPP4MEN1KMT2AHSD17B10
SCHEMBL19760099 0.85 ANPEP (0.33) ANPEPDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180071691-A1 Asymmetric Modified Carbon Molecular Sieve Hollow Fiber Membranes Having Improved Permeance AIR LIQUIDE ADVANCED TECHNOLOGIES U.S., LLC 2018-03-15 US disclosed
US-20180001270-A1 METALLOPOLYIMIDE PRECURSOR FIBERS FOR AGING-RESISTANT CARBON MOLECULAR SIEVE HOLLOW FIBER MEMBRANES WITH ENHANCED SELECTIVITY L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2018-01-04 US disclosed
US-20180001272-A1 METALLOPOLYIMIDE PRECURSOR FIBERS FOR AGING-RESISTANT CARBON MOLECULAR SIEVE HOLLOW FIBER MEMBRANES WITH ENHANCED SELECTIVITY L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2018-01-04 US disclosed
US-9815030-B2 Asymmetric modified carbon molecular sieve hollow fiber membranes having improved permeance SHELL OIL COMPANY (US) 2017-11-14 US disclosed
US-20160184776-A1 MANUFACTURING CARBON MOLECULAR SIEVE MEMBRANES USING A PYROLYSIS ATMOSPHERE COMPRISING SULFUR-CONTAINING COMPOUNDS AMERICAN AIR LIQUIDE, INC. 2016-06-30 US disclosed
US-20160151746-A1 COMPOSITE CARBON MOLECULAR SIEVE MEMBRANES HAVING ANTI-SUBSTRUCTURE COLLAPSE PARTICLES LOADED IN A CORE THEREOF AMERICAN AIR LIQUIDE, INC. 2016-06-02 US disclosed
US-20150094445-A1 Asymmetric Modified Carbon Molecular Sieve Hollow Fiber Membranes Having Improved Permeance AIR LIQUIDE ADVANCED TECHNOLOGIES U.S., LLC 2015-04-02 US disclosed
US-8709133-B2 Method for producing carbon molecular sieve membranes in controlled atmospheres GEORGIA TECH RESEARCH CORPORATION (US) 2014-04-29 US disclosed
US-20130305921-A1 METHOD FOR PRODUCING CARBON MOLECULAR SIEVE MEMBRANES IN CONTROLLED ATMOSPHERES AIR LIQUIDE ADVANCED TECHNOLOGIES U.S., LLC 2013-11-21 US disclosed
US-8486179-B2 Method for producing carbon molecular sieve membranes in controlled atmospheres GEORGIA TECH RESEARCH CORPORATION (US) 2013-07-16 US disclosed
US-20110100211-A1 METHOD FOR PRODUCING CARBON MOLECULAR SIEVE MEMBRANES IN CONTROLLED ATMOSPHERES AIR LIQUIDE ADVANCED TECHNOLOGIES U.S., LLC 2011-05-05 US disclosed