SCHEMBL7857161

SCHEMBL7857161

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCC[SiH](Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5475593 1.00
SCHEMBL1882796 0.98
SCHEMBL9398348 0.91
SCHEMBL2684886 0.86 LMNA (0.31)
SCHEMBL21907340 0.86 LMNA (0.31)
SCHEMBL7643019 0.84
SCHEMBL9398365 0.81
SCHEMBL17138283 0.78 LMNA (0.33)
SCHEMBL15495594 0.78 LMNA (0.38)
SCHEMBL25238564 0.76 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303730-B1 NONHYDROLYTIC CONDENSATION OF CHLOROSILANES WITH POLYMERIZABLE GROUPS AND OPTIONALLY FLUORINATED GROUPS, WITH THE HELP OF A CONDENSATION AGENT AND THERMAL AND/OR PHOTOCHEMICAL POLYMERIZATION OF THE OBTAINED CONDENSATION PRODUCT INSTITUT FUR NEUE MATERIALIEN GEMEINNUTZIGE GMBH (DE) 2001-10-16 US disclosed
US-6255516-B1 REACTING FLUORINE-CONTAINING OLEFINS WITH ORGANOSILICON COMPOUNDS IN THE PRESENCE OF KARSTEDT PLATINUM CATALYST; SURFACE-TREATING AGENTS HUELS AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed
US-5869728-A Process for preparing fluoroalkyl-containing organosilicon compounds, and their use HUELS AKTIENGESELLSCHAFT (DE) 1999-02-09 US disclosed