Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.61 |
| ▸ | CTSS | P25774 | 5/20 | 0.61 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978270 | 1.00 | CTSK (0.61) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL7355314 | 0.95 | CTSK (0.67) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL14272583 | 0.88 | CTSK (0.58) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL24298421 | 0.88 | CTSK (0.64) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL952036 | 0.88 | CTSK (0.64) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL952034 | 0.88 | CTSK (0.64) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL29414317 | 0.87 | CTSK (0.60) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL5025954 | 0.85 | CTSK (0.65) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9106410 | 0.85 | CTSK (0.65) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL6799683 | 0.85 | CTSK (0.65) | CTSKCTSSAAK1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595419-B2 | Process and intermediates for the preparation of 3-(amino)-3-cyclobutylmethyl-2-hydroxy-propionamide or salts thereof | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-20070237818-A1 | Controlled-release formulation of HCV protease inhibitor and methods using the same | SCHERING CORPORATION | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070237818-A1 | Controlled-release formulation of HCV protease inhibitor and methods using the same | CTRL, PEPD, PRCP | CTSK 103/4885CTSS 116/4885AAK1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.