Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16407914 | 0.87 | KDM1A (0.58) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL13272369 | 0.86 | KDM1A (0.58) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL21048167 | 0.85 | KDM1A (0.57) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL15540982 | 0.85 | KDM1A (0.57) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL15540980 | 0.85 | KDM1A (0.57) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL7904171 | 0.85 | KDM1A (0.57) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL17287408 | 0.84 | KDM1A (0.70) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL2564604 | 0.84 | KDM1A (0.70) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL4817372 | 0.84 | KDM1A (0.74) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL16155629 | 0.84 | KDM1A (0.74) | KDM1AMAOBMAOASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251910-B1 | 1,2,3-triazolo[4,5-d]pyrimidines as P2T receptor antagonists | ASTRAZENECA UK LIMITED (GB) | 2001-06-26 | — | — | US | disclosed |