Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180492 | 0.89 | TSHR (0.46) | TSHRFAAHZDHHC7GPR84FFAR1 | |
| SCHEMBL15477477 | 0.89 | TSHR (0.45) | TSHRFAAHZDHHC7GPR84CA1 | |
| SCHEMBL17541578 | 0.89 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL8197875 | 0.88 | TSHR (0.47) | TSHRFAAHZDHHC7GPR84FFAR1 | |
| SCHEMBL16180615 | 0.88 | TSHR (0.47) | TSHRFAAHZDHHC7GPR84FFAR1 | |
| SCHEMBL933010 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL9947731 | 0.81 | TSHR (0.44) | TSHRFAAHZDHHC7GPR84CA1 | |
| SCHEMBL9947943 | 0.80 | TSHR (0.46) | TSHRFAAHZDHHC7GPR84FFAR1 | |
| SCHEMBL28675357 | 0.80 | TSHR (0.46) | TSHRFAAHZDHHC7GPR84FFAR1 | |
| SCHEMBL1319101 | 0.80 | TSHR (0.46) | TSHRFAAHZDHHC7GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |