Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590437 | 0.75 | TSHR (0.36) | TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29777948 | 0.71 | TAAR1 (0.35) | TSHRLMNATAAR1 | |
| SCHEMBL3790257 | 0.68 | TSHR (0.45) | TSHRLMNAALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL3780980 | 0.68 | CYP3A4 (0.45) | TSHRALDH1A1CYP1A2NPC1HPGD | |
| 1,2-Dichlorobenzene SCHEMBL10593125 | 0.65 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL5190 | 0.65 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL29350623 | 0.65 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL1155123 | 0.65 | TSHR (1.00) | TSHRLMNAALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL14241619 | 0.65 | ALDH1A1 (0.43) | TSHRALDH1A1CYP2A6CYP1A2TP53 | |
| SCHEMBL13062132 | 0.64 | TSHR (0.43) | TSHRALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056822-B2 | Method for producing polycyclic aromatic compound substituted by aryl group | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-9056822-B2 | Method for producing polycyclic aromatic compound substituted by aryl group | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20140206908-A1 | METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-24 | — | — | US | disclosed |
| US-20140206908-A1 | METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-24 | — | — | US | disclosed |
| EP-2730554-A1 | METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP | National University Corporation Nagoya University (JP) | 2014-05-14 | — | — | EP | disclosed |
| WO-2012169635-A1 | METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP | 国立大学法人名古屋大学 (JP) | 2012-12-13 | — | — | WO | disclosed |
| EP-0736509-B1 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL CO (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6025531-A | REACTING A PROCHIRAL KETONE WITH A MIXTURE BORON-CONTAINING COMPOUNDS HAVING A BORANE REACTION PRODUCT FROM OPTICALLY ACTIVE BETA-AMINOALCOHOL AND A BORON HYDRIDE OR A METAL BOROHYDRIDE, AND AN OPTICALLY ACTIVE OXAZABOROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-15 | — | — | US | disclosed |
| US-5801280-A | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0736509-A2 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206908-A1 | METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP | PAH, DBH, AHR | TSHR 1850/4885LMNA 2723/4885ALDH1A1 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.