SCHEMBL7858673

SCHEMBL7858673

CC(C)(C)c1cc(O)ccc1-c1ccc(O)cc1C(C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
TYR P14679 3/20 0.67
ALOX15 P16050 2/20 0.67
LMNA P02545 2/20 0.67
HSD17B10 Q99714 2/20 0.67
NR1I2 O75469 1/20 0.67
CYP2C9 P11712 1/20 0.67
MIF P14174 1/20 0.67
HTT P42858 1/20 0.67
NFE2L2 Q16236 1/20 0.67
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
MAPT P10636 1/20 0.46
ATP2A2 P16615 1/20 0.46
ATP2A3 Q93084 1/20 0.46
DYRK1A Q13627 1/20 0.44
GAA P10253 1/20 0.43
CA2 P00918 3/20 0.42
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30629387 1.00 ALDH1A1 (0.67) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL7855632 0.87 HSD17B10 (0.57) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL7848525 0.87 ALDH1A1 (0.57) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL29156177 0.86 ALDH1A1 (0.57) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL3807871 0.85 HSD17B10 (0.55) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL28526907 0.83 ALOX5 (0.59) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL30753562 0.83 ALOX5 (0.59) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL7946603 0.83 ESR1 (0.48) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL2160202 0.82 ALDH1A1 (0.70) ALDH1A1TYRALOX15LMNAHSD17B10
SCHEMBL29091704 0.82 ALDH1A1 (0.52) ALDH1A1TYRALOX15LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640048-B Preparation method of 4,4' -biphenol 江苏新瀚新材料股份有限公司 2023-10-24 CN claimed
CN-116640048-A Preparation method of 4,4' -biphenol 江苏新瀚新材料股份有限公司 2023-08-25 CN claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
CN-116640048-B Preparation method of 4,4' -biphenol 江苏新瀚新材料股份有限公司 2023-10-24 CN disclosed
CN-116640048-A Preparation method of 4,4' -biphenol 江苏新瀚新材料股份有限公司 2023-08-25 CN disclosed
JP-2001089406-A METHOD OF PRODUCING p,p'-BIPHENOL SUMITOMO CHEM CO LTD 2001-04-03 JP disclosed
EP-0413415-A1 Carboxylic acids and derivates thereof The British Petroleum Company p.l.c. (GB) 1991-02-20 EP disclosed