Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582923 | 0.79 | ESR2 (0.48) | ESR2PLAUGAAHTTL3MBTL1 | |
| SCHEMBL25911560 | 0.76 | ESR2 (0.46) | ESR2PLAUGAAHTTL3MBTL1 | |
| SCHEMBL1664655 | 0.76 | ALDH1A1 (0.52) | ESR2PLAUGAAHTTL3MBTL1 | |
| SCHEMBL2629410 | 0.76 | ALDH1A1 (0.46) | ESR2GAAHTTPDGFRBPDGFRA | |
| SCHEMBL31731089 | 0.76 | ALDH1A1 (0.46) | ESR2GAAHTTPDGFRBPDGFRA | |
| SCHEMBL1598483 | 0.76 | BACE1 (0.57) | PLAUHTTALDH1A1MEN1KMT2A | |
| SCHEMBL6844962 | 0.76 | NCK1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4725394 | 0.76 | PIK3CG (0.53) | PDGFRBPDGFRAMAPTPIK3CGDYRK1A | |
| SCHEMBL29880393 | 0.76 | BACE1 (0.55) | PDGFRBPDGFRAALDH1A1MEN1KMT2A | |
| SCHEMBL28044781 | 0.75 | TLR9 (0.62) | ESR2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180632-B1 | USE OF THESE COMPOUNDS FOR TREATING DISORDERS/CONDITIONS INVOLVING CELLULAR DIFFERENTIATION, PROLIFERATION, EXTRACELLULAR MATRIX PRODUCTION OR MEDIATOR RELEASE AND/OR T CELL ACTIVATION AND PROLIFERATION | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-01-30 | — | — | US | disclosed |