Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364359 | 0.86 | TOP2A (0.51) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL2414088 | 0.77 | NPC1 (0.59) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL7362493 | 0.77 | RAB9A (0.50) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL3208241 | 0.76 | NPC1 (0.53) | RAB9ANPC1PKMLMNAALDH1A1 | |
| SCHEMBL30136183 | 0.75 | RAB9A (0.45) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL13588769 | 0.74 | RAB9A (0.46) | RAB9ANPC1PKMLMNAPOLB | |
| SCHEMBL7859968 | 0.74 | NPC1 (0.47) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL10860795 | 0.74 | MAPT (0.69) | MAPTTSHR | |
| SCHEMBL966665 | 0.74 | NPC1 (0.59) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL30058651 | 0.74 | NPC1 (0.59) | RAB9AMAPTNPC1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788362-B1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 2001-07-25 | — | — | EP | disclosed |
| CN-1048017-C | Phosphonocarboxylate compounds and pharmaceutical compositions containing the same | PROCTER & GAMBLE PHARMA (US) | 2000-01-05 | — | — | CN | disclosed |
| CN-1230409-A | Phosphonocarboxylate compounds and pharmaceutical compositions containing the same | PROCTER & GAMBLE PHARMA (US) | 1999-10-06 | — | — | CN | disclosed |
| CN-1224018-A | Phosphonic carboxylate compounds, pharmaceutical compositions contg. same | PROCTER & GAMBLE PHARMA (US) | 1999-07-28 | — | — | CN | disclosed |
| US-5760021-A | TREATING OR PREVENTING METABOLIC BONE DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0788362-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| CN-1089613-A | Phosphonocarboxylate compounds and pharmaceutical compositions containing the same | PROCTER & GAMBLE PHARMA (US) | 1994-07-20 | — | — | CN | disclosed |
| WO-1993024131-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |