Phosphine

Phosphine

SCHEMBL7860002

OB(Oc1ccccc1Cl)Oc1cccc2ccc3cc4ccccc4cc3c12.P

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.34
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 3/20 0.32
GAA P10253 2/20 0.32
CYP2A6 P11509 1/20 0.32
RXRA P19793 1/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL131517 0.92 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
Ammonia Solution, Strong SCHEMBL6841646 0.89 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL10425743 0.87 CYP1A2 (0.42) CYP1A2ERBB2FYNMAOAACHE
Phosphine SCHEMBL6661171 0.86 CYP1A2 (0.36) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL9443322 0.86 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
Phosphine SCHEMBL3288817 0.83 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
Ammonia Solution, Strong SCHEMBL9443279 0.82 CYP1A2 (0.38) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2013080 0.82 CYP1A2 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL6249069 0.82 PPARG (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL19259375 0.81 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1069146-A1 POLYCARBONATE AND OPTICAL MATERIAL Idemitsu Petrochemical Co., Ltd. (JP) 2001-01-17 EP disclosed
EP-1035150-A1 COPOLYCARBONATE AND PROCESS FOR PRODUCING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-09-13 EP disclosed