Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701605 | 0.82 | FDPS (0.51) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| SCHEMBL8706215 | 0.81 | FDPS (0.50) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| SCHEMBL9085173 | 0.76 | CPN1 (0.39) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| SCHEMBL9084192 | 0.76 | CPN1 (0.39) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| SCHEMBL8706218 | 0.76 | FDPS (0.42) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| SCHEMBL8712585 | 0.75 | CPN1 (0.35) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| SCHEMBL9806687 | 0.74 | FDPS (0.49) | SLC6A1SLC6A11SLC6A13LMNAGABRA5 | |
| SCHEMBL9084709 | 0.73 | KMT2A (0.42) | CPN1CPB2KMT2ASLC6A1SLC6A11 | |
| Iodide SCHEMBL9163644 | 0.72 | FDPS (0.39) | CPN1CPB2KMT2AEPHX1FDPS | |
| SCHEMBL7860170 | 0.72 | GFER (0.39) | SMN1; SMN2CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788362-B1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 2001-07-25 | — | — | EP | disclosed |
| US-5760021-A | TREATING OR PREVENTING METABOLIC BONE DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0788362-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| CN-1089613-A | Phosphonocarboxylate compounds and pharmaceutical compositions containing the same | PROCTER & GAMBLE PHARMA (US) | 1994-07-20 | — | — | CN | disclosed |
| WO-1993024131-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |