Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701605 | 0.81 | FDPS (0.51) | CPN1CPB2FDPSKMT2AEPHX1 | |
| SCHEMBL8706215 | 0.80 | FDPS (0.50) | CPN1CPB2FDPSKMT2AEPHX1 | |
| SCHEMBL9085173 | 0.75 | CPN1 (0.39) | CPN1CPB2FDPSKMT2AEPHX1 | |
| SCHEMBL9084192 | 0.75 | CPN1 (0.39) | CPN1CPB2FDPSAPLNRKMT2A | |
| SCHEMBL8706218 | 0.75 | FDPS (0.42) | CPN1CPB2FDPSKMT2AEPHX1 | |
| SCHEMBL7860079 | 0.75 | CPN1 (0.42) | CPN1CPB2FDPSKMT2AEPHX1 | |
| SCHEMBL9806687 | 0.73 | FDPS (0.49) | FDPSSLC6A1SLC6A11SLC6A13LMNA | |
| SCHEMBL8711893 | 0.72 | ATM (0.32) | SMN1; SMN2ATM | |
| SCHEMBL9084709 | 0.72 | KMT2A (0.42) | CPN1CPB2FDPSKMT2AEPHX1 | |
| SCHEMBL8717214 | 0.72 | FDPS (0.65) | FDPSKMT2ATSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1255501-A | Novel phosphonyl sulfonic ester compound and its medicinal compsns. | PROCTER & GAMBLE PHARMA (US) | 2000-06-07 | — | — | CN | disclosed |
| CN-1229083-A | Novel phosphononosulfonate compounds and its pharmaceutical compositions | PROCTER & GAMBLE PHARMA (US) | 1999-09-22 | — | — | CN | disclosed |
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5731299-A | OSTEOPOROSIS; RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0642518-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| CN-1087640-A | Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | PROCTER & GAMBLE PHARMA (US) | 1994-06-08 | — | — | CN | disclosed |
| WO-1993024495-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |