Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197287 | 0.87 | HRH3 (0.64) | LSSALDH1A1CHRM2HRH3TAAR1 | |
| Hydrochloric Acid SCHEMBL27816032 | 0.85 | HRH3 (0.61) | LSSALDH1A1CHRM2HRH3TAAR1 | |
| Methylene Chloride SCHEMBL6061380 | 0.83 | HRH3 (0.58) | LSSALDH1A1CHRM2HRH3TAAR1 | |
| SCHEMBL415949 | 0.82 | CHRM2 (0.67) | ALDH1A1CHRM2SMN1; SMN2KDM4ETHRB | |
| SCHEMBL4592721 | 0.81 | SIGMAR1 (0.56) | LSSTMEM97SIGMAR1CHRM2HRH3 | |
| SCHEMBL2056269 | 0.81 | HRH3 (0.77) | LSSALDH1A1HRH3TAAR1PYCR1 | |
| Dibromomethane SCHEMBL6061514 | 0.81 | HRH3 (0.56) | LSSALDH1A1CHRM2HRH3TAAR1 | |
| Hydrochloric Acid SCHEMBL7695180 | 0.80 | CHRM2 (0.64) | ALDH1A1CHRM2SMN1; SMN2KDM4ETHRB | |
| SCHEMBL23134289 | 0.79 | HRH3 (0.54) | LSSTMEM97SIGMAR1ALDH1A1HRH3 | |
| SCHEMBL10535689 | 0.78 | CHRM2 (0.58) | LSSTMEM97SIGMAR1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089965-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067204-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | disclosed |