Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.55 |
| ▸ | LSS | P48449 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27816032 | 0.97 | HRH3 (0.61) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| Methylene Chloride SCHEMBL6061380 | 0.95 | HRH3 (0.58) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| Dibromomethane SCHEMBL6061514 | 0.93 | HRH3 (0.56) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL2056269 | 0.93 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL10612102 | 0.87 | HRH3 (0.50) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL7860102 | 0.87 | LSS (0.58) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL659509 | 0.86 | HRH3 (0.82) | HRH3TAAR1ALDH1A1TSHRAOC3 | |
| Octane SCHEMBL10612108 | 0.85 | KCNH2 (0.51) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL18532755 | 0.84 | PYCR1 (0.67) | HRH3ALDH1A1TSHRPYCR1LSS | |
| SCHEMBL19389734 | 0.84 | LSS (0.58) | HRH3TAAR1ALDH1A1LSSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041819-B1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN | TAMINCO BVBA (BE) | 2020-05-13 | — | — | EP | claimed |
| US-10252979-B2 | Process for the reductive amination and selective hydrogenation of substrates containing a selected halogen | TAMINCO BVBA (BE) | 2019-04-09 | — | — | US | claimed |
| US-20170342019-A1 | PROCESS FOR THE REDUCTIVE AMINATION AND SELECTIVE HYDROGENATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN | TAMINCO BVBA (BE) | 2017-11-30 | — | — | US | claimed |
| CN-106034401-A | Improved process for reductive amination and selective hydrogenation of substrates containing selected halogens | 塔明克公司 | 2016-10-19 | — | — | CN | claimed |
| US-20160207874-A1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION AND SELECTIVE HYDROGENATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN | TAMINCO BVBA (BE) | 2016-07-21 | — | — | US | claimed |
| EP-3041819-A1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION AND SELECTIVE HYDROGENATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN | Taminco bvba (BE) | 2016-07-13 | — | — | EP | claimed |
| WO-2015032653-A1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION AND SELECTIVE HYDROGENATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN | TAMINCO (BE) | 2015-03-12 | — | — | WO | claimed |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | claimed |
| WO-2008100618-A2 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| CN-117531520-A | Catalyst and preparation method and application thereof | 厦门大学 | 2024-02-09 | — | — | CN | disclosed |
| WO-2024027109-A1 | CATALYST, PREPARATION METHOD THEREFOR AND USE THEREOF | XIAMEN UNIVERSITY (CN) | 2024-02-08 | — | — | WO | disclosed |
| EP-3374344-B1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION OF HALOGEN-CONTAINING SUBSTRATES | TAMINCO BV (BE) | 2023-10-04 | — | — | EP | disclosed |
| CN-114436851-B | Preparation method of N, N-dimethylbenzylamine and derivatives thereof | 常州大学 | 2023-08-22 | — | — | CN | disclosed |
| US-11718614-B2 | Compounds and methods for treatment of hedgehog pathway associated conditions | SUZHOU MEDNES PHARMA TECH CO., LTD. (CN) | 2023-08-08 | — | — | US | disclosed |
| US-4099012-A | ANTIANXIETY, ANTIDEPRESSANT | CIBA-GEIGY CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4028381-A | ANTIANXIETY AND ANTIDEPRESSANT AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-4022801-A | ANTIANXIETY AND ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4022800-A | ANTIANXIETY AND ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-3947585-A | ANTIANXIETY, ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3939271-A | Antidepressive and antianxiety composition comprising 2-pyrazolyl-benzophenones | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718614-B2 | Compounds and methods for treatment of hedgehog pathway associated conditions | SHH, GLI1, SMO | HRH3 1229/4885TAAR1 3479/4885ALDH1A1 786/4885 |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | CTSS, CTSK, CTSZ | HRH3 354/4885TAAR1 3251/4885ALDH1A1 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.