Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517280 | 0.95 | DGKA (0.46) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL11352492 | 0.95 | DGKA (0.52) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL3516020 | 0.93 | DGKA (0.50) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL11357831 | 0.93 | DGKA (0.56) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL11169949 | 0.92 | ADRA2A (0.46) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL2868536 | 0.91 | DGKA (0.54) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL3516269 | 0.90 | DGKA (0.41) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL30517203 | 0.90 | DGKA (0.46) | DGKADNM1TSHRADRA2AADRA1A | |
| SCHEMBL26871450 | 0.89 | DGKA (0.59) | DGKADNM1TSHRMAPTHTR2C | |
| SCHEMBL3517120 | 0.88 | DGKA (0.50) | DGKADNM1TSHRADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018302-A1 | BIORESORBABLE, STEREOCHEMICALLY DEFINED ELASTOMERS AND METHODS OF MAKING AND USING SAME | UNIV DUKE (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018302-A1 | BIORESORBABLE, STEREOCHEMICALLY DEFINED ELASTOMERS AND METHODS OF MAKING AND USING SAME | UNIV DUKE (US) | 2024-01-18 | — | — | US | disclosed |
| US-20230383056-A1 | BIORESORBABLE,STEREOCHEMICALLY DEFINED ELASTOMERS AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230383056-A1 | BIORESORBABLE,STEREOCHEMICALLY DEFINED ELASTOMERS AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2023-11-30 | — | — | US | disclosed |
| EP-1093453-A1 | NAALADASE INHIBITORS USEFUL AS PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS | GUILFORD PHARMACEUTICALS INC. (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000001668-A2 | NAALADASE INHIBITORS USEFUL AS PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-01-13 | — | — | WO | disclosed |