Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinylsulfonic Acid SCHEMBL4897834 | 0.98 | ALDH1A1 (0.35) | POLBSMN1; SMN2HSD17B10ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL28627994 | 0.87 | POLB (0.39) | POLBSMN1; SMN2HSD17B10ALDH1A1CXCR4 | |
| Sulfuric Acid SCHEMBL8846690 | 0.87 | POLB (0.42) | POLBSMN1; SMN2HSD17B10ALDH1A1CXCR4 | |
| SCHEMBL3862299 | 0.83 | HSD17B10 (0.43) | POLBSMN1; SMN2HSD17B10ALDH1A1CXCR4 | |
| Sulfuric Acid SCHEMBL29010960 | 0.83 | POLB (0.39) | POLBSMN1; SMN2HSD17B10ALDH1A1CXCR4 | |
| SCHEMBL83682 | 0.81 | POLB (0.38) | POLBSMN1; SMN2HSD17B10ALDH1A1MAPT | |
| SCHEMBL28790654 | 0.81 | POLB (0.38) | POLBSMN1; SMN2HSD17B10ALDH1A1MAPT | |
| SCHEMBL28478814 | 0.81 | POLB (0.38) | POLBSMN1; SMN2HSD17B10ALDH1A1CXCR4 | |
| Ethylene SCHEMBL28756284 | 0.80 | POLB (0.46) | POLBSMN1; SMN2HSD17B10ALDH1A1MAPT | |
| SCHEMBL8373240 | 0.80 | POLB (0.50) | POLBSMN1; SMN2HSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306858-B1 | ANTIINFLAMMATORY AGENTS FOR MUSCLE INFLAMMATION BY APPLING TO SKIN | PUGLIESE PETER T (US) | 2001-10-23 | — | — | US | disclosed |
| EP-1033913-A1 | ZWITTERIONIC FATTY ACID COMPOUNDS FOR ANTI-INFLAMATION | Pugliese, Peter T. (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999027791-A1 | ZWITTERIONIC FATTY ACID COMPOUNDS FOR ANTI-INFLAMATION | PUGLIESE PETER T (US) | 1999-06-10 | — | — | WO | disclosed |