Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857029 | 0.99 | HTR1A (0.52) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7615691 | 0.94 | HTR1A (0.54) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7615682 | 0.94 | HTR1A (0.54) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7617997 | 0.93 | HTR1A (0.55) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7618009 | 0.93 | HTR1A (0.55) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7859098 | 0.89 | HTR1A (0.59) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7857717 | 0.88 | HTR1A (0.40) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7857729 | 0.88 | HTR1A (0.60) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7857726 | 0.87 | DRD2 (0.44) | HTR1ADRD2HTR1DDRD3SLC6A4 | |
| SCHEMBL7857811 | 0.86 | DRD2 (0.43) | HTR1ADRD2HTR1DDRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725779-B1 | NOVEL (R)-5-CARBAMOYL-8-FLUORO-3-N,N-DISUBSTITUTED-AMINO-3,4-DIHYDRO-2H-1-BENZOPYRANES | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | disclosed |