Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857119 | 0.83 | CYP1A2 (0.55) | MGAMRAB9AKDM4ESMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL22608806 | 0.82 | HAO1 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL29490682 | 0.82 | HAO1 (0.49) | — | |
| SCHEMBL27633359 | 0.82 | ALDH1A1 (0.55) | MGAMRAB9AKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL31238886 | 0.82 | ALDH1A1 (0.55) | MGAMRAB9AKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL27455343 | 0.82 | MGAM (0.47) | MGAMRAB9AKDM4ESMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL9693430 | 0.80 | MGAM (0.81) | MGAMRAB9AKDM4ESMN1; SMN2KDR | |
| Trifluoroacetic Acid SCHEMBL30684640 | 0.80 | MGAM (0.53) | MGAMRAB9AKDM4ESMN1; SMN2KDR | |
| Trifluoroacetic Acid SCHEMBL8360271 | 0.78 | MGAM (0.62) | MGAMRAB9AKMT2AKDRCYP3A4 | |
| SCHEMBL2345799 | 0.78 | MGAM (0.57) | MGAMRAB9AKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |