Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860916 | 0.83 | DRD4 (0.32) | TTRDRD4 | |
| SCHEMBL6932578 | 0.81 | PPARA (0.35) | LPAR1LPAR5 | |
| SCHEMBL6932576 | 0.81 | PPARA (0.35) | LPAR1LPAR5 | |
| SCHEMBL6935483 | 0.79 | MAPK14 (0.39) | LPAR1LPAR5 | |
| SCHEMBL6935487 | 0.79 | MAPK14 (0.39) | LPAR1LPAR5 | |
| SCHEMBL7860919 | 0.78 | LPAR1 (0.33) | LPAR1LPAR5 | |
| SCHEMBL7862126 | 0.76 | SMN1; SMN2 (0.32) | TTR | |
| SCHEMBL8418431 | 0.66 | SRD5A2 (0.38) | LPAR1LPAR5 | |
| SCHEMBL13888115 | 0.66 | TTR (0.47) | TTRLPAR1LPAR5 | |
| SCHEMBL11091463 | 0.65 | TTR (0.39) | TTRLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131273-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2001-09-12 | — | — | EP | claimed |
| WO-2000029362-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | claimed |
| EP-1131273-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029362-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |