Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932578 | 1.00 | PPARA (0.35) | PPARAPPARGLPAR1LPAR5L3MBTL1 | |
| SCHEMBL6935483 | 0.89 | MAPK14 (0.39) | LPAR1LPAR5SMN1; SMN2HPGDLTA4H | |
| SCHEMBL6935487 | 0.89 | MAPK14 (0.39) | LPAR1LPAR5SMN1; SMN2HPGDLTA4H | |
| SCHEMBL8418431 | 0.83 | SRD5A2 (0.38) | LPAR1LPAR5L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7860917 | 0.81 | TTR (0.31) | LPAR1LPAR5 | |
| SCHEMBL7860919 | 0.81 | LPAR1 (0.33) | LPAR1LPAR5 | |
| SCHEMBL7860916 | 0.81 | DRD4 (0.32) | — | |
| SCHEMBL6932505 | 0.73 | LMNA (0.35) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6935659 | 0.73 | LMNA (0.35) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6230685 | 0.72 | LMNA (0.34) | L3MBTL1LMNASMN1; SMN2GAAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131273-B1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-10-22 | — | — | EP | claimed |
| US-6342642-B1 | DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | claimed |
| EP-1202948-B1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| EP-1131273-B1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6342642-B1 | DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6291721-B1 | REACTING 2-ARYL ALDEHYDE COMPOUND WITH ALCOHOL OR HEATING ACETAL COMPOUND IN PRESENCE OF APROTIC SOLVENT TO PRODUCE2-ARYLVINYL ETHER COMPOUND | AMERICAN CYANAMID CO. | 2001-09-18 | — | — | US | disclosed |