Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935483 | 1.00 | MAPK14 (0.39) | MAPK14MEN1KMT2AFFAR1LPAR1 | |
| SCHEMBL6932578 | 0.89 | PPARA (0.35) | LPAR1LPAR5PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL6932576 | 0.89 | PPARA (0.35) | LPAR1LPAR5PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL7860919 | 0.79 | LPAR1 (0.33) | LPAR1LPAR5 | |
| SCHEMBL7860916 | 0.79 | DRD4 (0.32) | — | |
| SCHEMBL7860917 | 0.79 | TTR (0.31) | LPAR1LPAR5 | |
| SCHEMBL6934678 | 0.75 | CXCL12 (0.38) | MAPK14 | |
| SCHEMBL6934681 | 0.75 | CXCL12 (0.38) | MAPK14 | |
| SCHEMBL8418431 | 0.73 | SRD5A2 (0.38) | LPAR1LPAR5HPGDSMN1; SMN2LTA4H | |
| SCHEMBL7205195 | 0.70 | FFAR1 (0.35) | MAPK14MEN1KMT2AFFAR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131273-B1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-10-22 | — | — | EP | claimed |
| US-6342642-B1 | DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | claimed |
| EP-1202948-B1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| EP-1131273-B1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-10-22 | — | — | EP | disclosed |
| EP-1202948-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| US-6342642-B1 | DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6291721-B1 | REACTING 2-ARYL ALDEHYDE COMPOUND WITH ALCOHOL OR HEATING ACETAL COMPOUND IN PRESENCE OF APROTIC SOLVENT TO PRODUCE2-ARYLVINYL ETHER COMPOUND | AMERICAN CYANAMID CO. | 2001-09-18 | — | — | US | disclosed |
| EP-1131273-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001012578-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000029362-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |