Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.60 |
| ▸ | MGAM | O43451 | 9/20 | 0.59 |
| ▸ | GAA | P10253 | 9/20 | 0.59 |
| ▸ | SI | P14410 | 9/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141034 | 0.82 | PARP1 (0.72) | PARP1 | |
| SCHEMBL7861250 | 0.81 | MGAM (0.56) | VSIRMGAMGAASIMGAM2 | |
| SCHEMBL6378984 | 0.79 | PARP1 (0.51) | VSIRMMP2MMP9MMP8MMP13 | |
| SCHEMBL7861251 | 0.78 | PARP1 (0.55) | VSIRMGAMGAASIMGAM2 | |
| SCHEMBL5074029 | 0.75 | MGAM (0.76) | MGAMGAASIMGAM2HPSE | |
| SCHEMBL30615069 | 0.75 | MGAM (0.76) | MGAMGAASIMGAM2HPSE | |
| SCHEMBL3341620 | 0.73 | HTR7 (0.61) | KDM4EALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL1170892 | 0.72 | MGAM (0.71) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL7854331 | 0.72 | MGAM (0.58) | VSIRMGAMGAASIMGAM2 | |
| SCHEMBL7047918 | 0.72 | MGAM (0.68) | MGAMGAASIMGAM2HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131301-A1 | 2-PHENYLBENZIMIDAZOLES AND 2-PHENYLINDOLES, AND PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029384-A1 | 2-PHENYLBENZIMIDAZOLES AND 2-PHENYLINDOLES, AND PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |