SCHEMBL7861370

SCHEMBL7861370

COCOc1ccc(CCOC=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HRH3 Q9Y5N1 2/20 0.38
ADRB2 P07550 2/20 0.38
ADRB1 P08588 2/20 0.38
NR3C1 P04150 1/20 0.38
CYP2D6 P10635 1/20 0.38
ADRA1A P35348 1/20 0.38
CYP2J2 P51589 1/20 0.38
PDE4D Q08499 1/20 0.38
FFAR1 O14842 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ENPP2 Q13822 1/20 0.37
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
PMP22 Q01453 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9532705 0.82 TAAR1 (0.52) ALDH1A1MAPTSMN1; SMN2
SCHEMBL5674310 0.79 FFAR1 (0.37) LMNAALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL5535271 0.78 FFAR1 (0.61) HPGDFFAR1PPARGPPARA
SCHEMBL7866228 0.77 FFAR1 (0.40) LMNASMN1; SMN2HRH3FFAR1L3MBTL1
SCHEMBL7861366 0.77 HRH3 (0.38) LMNAALDH1A1HRH3ADRB2ADRB1
SCHEMBL12769822 0.76 THRB (0.49) LMNAALDH1A1HPGDFFAR1L3MBTL1
SCHEMBL5543897 0.75 FFAR1 (0.58) LMNAFFAR1
SCHEMBL23836740 0.75 PPARA (0.41) PPARGPPARA
SCHEMBL11009805 0.74 CYP2A6 (0.45) ALDH1A1HRH3L3MBTL1TDP1
SCHEMBL2128463 0.74 ALDH1A1 (0.47) LMNAALDH1A1HRH3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623608-B1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LTD (JP) 2001-05-30 EP disclosed
EP-0623608-A1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1994-11-09 EP disclosed