Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203682 | 0.77 | PPARA (0.51) | PPARAPPARGL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9201161 | 0.70 | PPARG (0.51) | PPARAPPARGL3MBTL1MAPTPOLB | |
| SCHEMBL6739237 | 0.67 | PPARG (0.63) | PPARAPPARGMAPTPOLBALDH1A1 | |
| SCHEMBL6739239 | 0.67 | PPARG (0.63) | PPARAPPARGMAPTPOLBALDH1A1 | |
| SCHEMBL9204724 | 0.67 | PPARG (0.47) | PPARAPPARGTP53MAPTPOLB | |
| SCHEMBL6740655 | 0.66 | PPARG (0.77) | PPARAPPARGALDH1A1MEN1KMT2A | |
| SCHEMBL7323206 | 0.66 | ALDH1A1 (0.48) | MAPTSMN1; SMN2TDP1ALDH1A1MEN1 | |
| SCHEMBL9205410 | 0.66 | PPARG (0.50) | PPARAPPARGL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL9202605 | 0.66 | PPARG (0.50) | PPARAPPARGL3MBTL1POLBLMNA | |
| SCHEMBL6737620 | 0.65 | PPARG (0.71) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |