Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.51 |
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202605 | 0.88 | PPARG (0.50) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL9205874 | 0.87 | PPARG (0.47) | PPARAPPARGLMNAL3MBTL1TDP1 | |
| SCHEMBL9201161 | 0.83 | PPARG (0.51) | PPARAPPARGLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7860020 | 0.81 | L3MBTL1 (0.53) | PPARAPPARGLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7854550 | 0.79 | PPARG (0.46) | PPARAPPARGLMNAL3MBTL1TDP1 | |
| SCHEMBL9205410 | 0.78 | PPARG (0.50) | PPARAPPARGLMNAL3MBTL1TDP1 | |
| SCHEMBL7861377 | 0.77 | PPARA (0.41) | PPARAPPARGLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9204724 | 0.76 | PPARG (0.47) | PPARAPPARGLMNAKMT2AKDM4E | |
| SCHEMBL9205464 | 0.75 | L3MBTL1 (0.48) | PPARAPPARGLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL28840979 | 0.75 | TDP1 (0.48) | PPARGL3MBTL1TDP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |