Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24872545 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL16953179 | 0.80 | S1PR1 (0.42) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL20838005 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL16949914 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL12648426 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL10891656 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL16680739 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL186269 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL13780122 | 0.77 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL1154535 | 0.76 | HTR2A (0.43) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| US-6121287-A | Quinoline derivatives | ACTIVE BIOTECH AB (SE) | 2000-09-19 | — | — | US | disclosed |
| WO-2000003992-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |