SCHEMBL186269

SCHEMBL186269

N#Cc1c(F)cccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
KDM4E B2RXH2 5/20 0.50
TRPV4 Q9HBA0 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPT P10636 2/20 0.41
CUL4A Q13619 1/20 0.41
EGLN2 Q96KS0 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
DRD2 P14416 1/20 0.38
HTR2A P28223 1/20 0.38
HRH1 P35367 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanide SCHEMBL28871133 0.95 ALDH1A1 (0.47) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL19062287 0.87 ALDH1A1 (0.46) ALDH1A1KDM4ETRPV4HPGDHSD17B10
Dichlobenil SCHEMBL28814465 0.86 KDM4E (0.46) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL186554 0.85 KDM4E (0.44) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL20159004 0.83 ALDH1A1 (0.43) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL525892 0.83 ALDH1A1 (0.43) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL286715 0.83 CYP1A2 (0.50) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL421862 0.83 ALDH1A1 (0.43) ALDH1A1KDM4ETRPV4HPGDHSD17B10
SCHEMBL186023 0.83 KDM4E (0.47) ALDH1A1KDM4EHPGDHSD17B10TAS1R3
SCHEMBL3154084 0.83 ALDH1A1 (0.43) ALDH1A1KDM4ETRPV4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2332 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-224278285-U 2, 6-Difluorobenzonitrile stable storage cold chain device JINING KANGSHENG CAIHONG BIOTECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-120748821-B Surface wear-resistant cable and preparation method thereof Guangdong Zhongbao Cable Co.,Ltd. (CN) 2026-05-26 CN claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
CN-120192521-A High molecular weight crystallization type polyarylether nitrile and preparation method thereof 电子科技大学 2025-06-24 CN claimed
CN-120137499-A Preparation method of novel tough epoxy resin anti-corrosion coating 大连理工大学 2025-06-13 CN claimed
CN-119905773-A Preparation method and application of high-performance polyarylether battery diaphragm 成都大学 2025-04-29 CN claimed
CN-119410557-B Rhodococcus ruber and application thereof 天津科技大学 2025-04-08 CN claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-119529266-A Synthesis method of narrow-distribution phenolphthalein polyaryletherketone/sulfone 浙江帕尔科新材料有限公司 2025-02-28 CN claimed
US-4663427-A Process for preparing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-05-05 US claimed
EP-0186153-A2 Process for preparing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1986-07-02 EP claimed
EP-0073372-B1 PROCESS FOR PRODUCING 2,6-DIFLUOROBENZONITRILE ISHIHARA SANGYO KAISHA, LTD. (JP) 1984-08-01 EP claimed
US-4438042-A FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-03-20 US claimed
US-4436669-A CYANATION, DECARBONYLATION, ACID CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-03-13 US claimed
EP-0053247-B1 PROCESS FOR PREPARATION OF 6-FLUORO-ANTHRANILIC ACID NITRILE OR 6-FLUORO-ANTHRANILIC ACID AND 6-FLUORO-ANTHRANILIC ACID NITRILE BASF Aktiengesellschaft (DE) 1984-01-18 EP claimed
US-4406841-A HYDROGENATION OF 3-CHLORO- (OR 3,5-DICHLORO-2,6-DIFLUOROBENZONITRILE, PALLADIUM OR PLATINUM CATALYST ISHIHARA SANGYO KAISHA LTD. (JP) 1983-09-27 US claimed
EP-0073372-A1 Process for producing 2,6-difluorobenzonitrile ISHIHARA SANGYO KAISHA, LTD. (JP) 1983-03-09 EP claimed
US-4359428-A Preparation of fluorinated anthranilic acid and anthranilonitrile BASF AKTIENGESELLSCHAFT (DE) 1982-11-16 US claimed
EP-0053247-A1 Process for preparation of 6-fluoro-anthranilic acid nitrile or 6-fluoro-anthranilic acid and 6-fluoro-anthranilic acid nitrile BASF Aktiengesellschaft (DE) 1982-06-09 EP claimed