Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110039 | 0.90 | CYP3A4 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL23360658 | 0.88 | LMNA (0.43) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL3030454 | 0.88 | CYP3A4 (0.48) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL7205358 | 0.86 | LMNA (0.45) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL96307 | 0.86 | CYP3A4 (0.55) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL7209537 | 0.86 | LMNA (0.45) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL7204580 | 0.86 | LMNA (0.45) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL8634225 | 0.84 | LMNA (0.41) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL10527246 | 0.83 | PRSS1 (0.42) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL5739082 | 0.80 | LMNA (0.39) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623608-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0623608-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1994-11-09 | — | — | EP | disclosed |