Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868091 | 0.73 | AOC3 (0.33) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL5379969 | 0.71 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1MAPK1PKMCTNNB1 | |
| SCHEMBL3739271 | 0.71 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1MAPK1MAPTCYP3A4 | |
| SCHEMBL7216296 | 0.69 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1MAPK1PKMCTNNB1 | |
| SCHEMBL30617194 | 0.69 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1MAPK1PKMCTNNB1 | |
| SCHEMBL1751672 | 0.69 | AHR (0.53) | SMN1; SMN2ALDH1A1MAPK1PKMMAPT | |
| SCHEMBL29061284 | 0.67 | CYP3A4 (0.44) | SMN1; SMN2ALDH1A1MAPK1PKMCTNNB1 | |
| SCHEMBL9016652 | 0.65 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPK1PKMMAPT | |
| SCHEMBL11832759 | 0.65 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPK1PKMMAPT | |
| SCHEMBL30513558 | 0.64 | CYP3A4 (0.46) | SMN1; SMN2ALDH1A1MAPK1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1342156-A | Inhibition and treatment of hepatitis B virus and flavivirus by helioxanthin and its analogs | UNIV YALE (US) | 2002-03-27 | — | — | CN | disclosed |
| US-6306899-B1 | VIRICIDES | YALE UNIVERSITY | 2001-10-23 | — | — | US | disclosed |
| EP-1107961-A1 | INHIBITION AND TREATMENT OF HEPATITIS B VIRUS AND FLAVIVIRUS BY HELIOXANTHIN AND ITS ANALOGS | YALE UNIVERSITY (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000010991-A1 | INHIBITION AND TREATMENT OF HEPATITIS B VIRUS AND FLAVIVIRUS BY HELIOXANTHIN AND ITS ANALOGS | YALE UNIVERSITY (US) | 2000-03-02 | — | — | WO | disclosed |