Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861452 | 0.73 | SMN1; SMN2 (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8078912 | 0.64 | TARBP2 (0.39) | MEN1KMT2ACYP3A4 | |
| SCHEMBL15782882 | 0.64 | AOC3 (0.40) | AOC3MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8998717 | 0.63 | AOC3 (0.49) | AOC3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6542530 | 0.63 | CYP3A4 (0.39) | AOC3MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL17522052 | 0.62 | AOC3 (0.63) | AOC3CYP3A4 | |
| SCHEMBL12553106 | 0.61 | AOC3 (0.36) | AOC3CYP3A4CYP2D6 | |
| SCHEMBL9786001 | 0.61 | AOC3 (0.40) | AOC3CYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL3861593 | 0.61 | MEN1 (0.30) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19124066 | 0.60 | KDM4E (0.40) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306899-B1 | VIRICIDES | YALE UNIVERSITY | 2001-10-23 | — | — | US | disclosed |
| EP-1107961-A1 | INHIBITION AND TREATMENT OF HEPATITIS B VIRUS AND FLAVIVIRUS BY HELIOXANTHIN AND ITS ANALOGS | YALE UNIVERSITY (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000010991-A1 | INHIBITION AND TREATMENT OF HEPATITIS B VIRUS AND FLAVIVIRUS BY HELIOXANTHIN AND ITS ANALOGS | YALE UNIVERSITY (US) | 2000-03-02 | — | — | WO | disclosed |