Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482817 | 0.80 | SLC6A4 (0.48) | TSHRMAPTHSD17B10SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4795565 | 0.79 | SLC6A4 (0.47) | TSHRMAPTHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL18228582 | 0.78 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL19310680 | 0.77 | SLC6A4 (0.46) | KDM4ETSHRMAPTHSD17B10SLC6A2 | |
| SCHEMBL3686055 | 0.76 | CYP11B2 (0.49) | KDM4ETSHRMAPTHSD17B10SLC6A2 | |
| SCHEMBL18239433 | 0.75 | ALDH1A1 (0.41) | KDM4ETSHRMAPTHSD17B10SLC6A2 | |
| SCHEMBL3298145 | 0.73 | SLC6A4 (0.55) | SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL6583550 | 0.73 | GAA (0.56) | KDM4ETSHRMAPTHSD17B10SLC6A2 | |
| SCHEMBL18228087 | 0.72 | ADORA2A (0.45) | TSHRALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18228622 | 0.72 | SMYD3 (0.47) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683792-B1 | LHRH ANTAGONISTS HAVING MODIFIED AMINOACYL RESIDUES AT POSTIONS 5 AND 6 | ABBOTT LAB (US) | 2001-09-26 | — | — | EP | disclosed |