SCHEMBL7861491

SCHEMBL7861491

CCC(CCCl)CCCCCCl

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 2/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.34
CA2 P00918 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20903956 0.90 ALDH1A1 (0.48) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18107415 0.88 ALDH1A1 (0.62) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18107452 0.88 LMNA (0.50) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18107323 0.88 LMNA (0.50) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18107450 0.88 LMNA (0.50) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18107363 0.88 LMNA (0.50) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18184661 0.88 ALDH1A1 (0.62) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18107253 0.85 ALDH1A1 (0.46) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL18184497 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL11676287 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0740679-B1 CROSSLINKED POLYMERIC AMMONIUM SALTS DU PONT (US) 2001-08-08 EP claimed
US-5874522-A FORMING CROSSLINKED POLYMERIC AMMONIUM SALT OR POLYMERIC AMINE IN SOLVENT, WHEREIN TEMPLATE COMPRISING SACCHARIDE OR ORGANIC METAL SALT IS PRESENT WHEN THE CROSSLINKED POLYMERIC AMMONIUM SALT OR POLYMERIC AMINE GELS; BILE ACID SEQUESTRANTS DUPONT PHARMACEUTICALS COMPANY (US) 1999-02-23 US claimed
US-5726284-A Crosslinked polymric ammonium salts THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1998-03-10 US claimed
EP-0740679-A1 CROSSLINKED POLYMERIC AMMONIUM SALTS E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1996-11-06 EP claimed
US-5556619-A BILE ACID SEQUESTERANTS TO LOWER BLOOD CHOLESTEROL, POLYAMINES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-17 US claimed
WO-1995019384-A1 CROSSLINKED POLYMERIC AMMONIUM SALTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-20 WO claimed