Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873041 | 0.95 | PARP1 (0.42) | NAMPTPARP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7869029 | 0.91 | SCD (0.41) | NAMPTALDH1A1RXFP1PRKAB2PRKAG1 | |
| SCHEMBL7869019 | 0.90 | ADRA2A (0.44) | NAMPTALDH1A1RXFP1PRKAB2PRKAG1 | |
| SCHEMBL7873099 | 0.89 | PARP1 (0.45) | PARP1ALDH1A1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7873048 | 0.88 | PARP1 (0.40) | NAMPTPARP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL8491991 | 0.87 | PARP1 (0.42) | NAMPTPARP1ALDH1A1PRKAB2PRKAG1 | |
| SCHEMBL7868110 | 0.86 | PARP1 (0.47) | PARP1ALDH1A1PRKAB2PRKAG1PRKAA2 | |
| Hydrochloric Acid SCHEMBL7869121 | 0.86 | PARP1 (0.41) | NAMPTPARP1ALDH1A1PRKAB2PRKAG1 | |
| SCHEMBL7872872 | 0.85 | SCD (0.42) | NAMPTPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7861532 | 0.85 | NAMPT (0.44) | NAMPTPARP1ALDH1A1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |