Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.49 |
| ▸ | PDE4A | P27815 | 8/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529001 | 0.90 | PDE4B (0.62) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7866726 | 0.88 | MMP13 (0.55) | PDE4BPDE4APDE4CPDE4DMMP13 | |
| SCHEMBL11993041 | 0.88 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DMMP13 | |
| SCHEMBL7862771 | 0.83 | PDE4B (0.54) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7862585 | 0.82 | PDE4B (0.50) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7861597 | 0.81 | HPGD (0.60) | PDE4BPDE4APDE4CPDE4DMMP13 | |
| SCHEMBL7862102 | 0.79 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11993028 | 0.78 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7863402 | 0.78 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11993086 | 0.78 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | NFKBIA, LITAF, CD68 | ALDH1A1 3761/4885PDE4B 776/4885PDE4A 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.