SCHEMBL786167

SCHEMBL786167

CCCCCNC(=N)NC(=N)N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 4/20 0.44
EPHX1 P07099 7/20 0.43
SPHK2 Q9NRA0 1/20 0.40
CASP2 P42575 1/20 0.39
DPP7 Q9UHL4 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
NAAA Q02083 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL28145190 1.00 SPHK1 (0.44) SPHK1EPHX1SPHK2CASP2DPP7
SCHEMBL1428105 0.98 EPHX1 (0.47) SPHK1EPHX1SPHK2CASP2MEN1
Polihexanide SCHEMBL45011 0.98 EPHX1 (0.47) SPHK1EPHX1SPHK2CASP2MEN1
SCHEMBL4111428 0.98 EPHX1 (0.47) SPHK1EPHX1SPHK2CASP2MEN1
SCHEMBL5133441 0.98 EPHX1 (0.47) SPHK1EPHX1SPHK2CASP2MEN1
SCHEMBL245909 0.98 EPHX1 (0.47) SPHK1EPHX1SPHK2CASP2MEN1
SCHEMBL3921623 0.98 EPHX1 (0.47) SPHK1EPHX1SPHK2CASP2MEN1
Polihexanide SCHEMBL115297 0.96 SPHK1 (0.49) SPHK1EPHX1SPHK2CASP2MEN1
Hydrochloric Acid SCHEMBL1900717 0.96 SPHK1 (0.49) SPHK1EPHX1SPHK2CASP2MEN1
Hydrochloric Acid SCHEMBL8898546 0.96 SPHK1 (0.49) SPHK1EPHX1SPHK2CASP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111773439-B Biological friendly antibacterial coating capable of effectively fixing cationic antibacterial agent and resisting bacterial biofilm 陕西师范大学 2022-03-04 CN claimed
CN-111773439-A Biological friendly antibacterial coating capable of effectively fixing cationic antibacterial agent and resisting bacterial biofilm 陕西师范大学 2020-10-16 CN claimed
CN-106340386-B A kind of large capacity thin film capacitor 安徽飞达电气科技有限公司 2018-06-01 CN claimed
CN-106340386-A High-capacity film capacitor 安徽飞达电气科技有限公司 2017-01-18 CN claimed
US-20160160447-A1 Guanidyl Paper Coating Polymer Ventures Inc. (US) 2016-06-09 US claimed
US-8631868-B1 Treatment of subterranean formations Polymer Ventures Inc. (US) 2014-01-21 US claimed
US-8220565-B1 Treatment of subterranean formations POLYMER VENTURES, INC. (US) 2012-07-17 US claimed
US-20120160485-A1 Treatment of Subterranean Formations POLYMER VENTURES, INC. (US) 2012-06-28 US claimed
EP-1670645-B1 BIGUANIDE BLEACHING AGENT FOR THERMAL-IMAGING EASTMAN KODAK CO (US) 2012-05-02 EP claimed
US-8157010-B2 Treatment of subterranean formations POLYMER VENTURES, INC. (US) 2012-04-17 US claimed
US-20120067585-A1 TREATMENT OF SUBTERRANEAN FORMATIONS WATER MARK TECHNOLOGIES, INC. (US) 2012-03-22 US claimed
CN-1730725-B Surface treatment method for flux-brazed aluminum-made heat exchanger NIPPON PAINT CO LTD 2010-06-23 CN claimed
US-7172992-B2 Biguanide bleaching agent for a thermal-imaging receptor element EASTMAN KODAK COMPANY (US) 2007-02-06 US claimed
EP-1670645-A1 BIGUANIDE BLEACHING AGENT FOR A THERMAL-IMAGING RECEPTOR ELEMENT Kodak Polychrome Graphics (US) 2006-06-21 EP claimed
US-20050181943-A1 Biguanide bleaching agent for a thermal-imaging receptor element KODAK POLYCHROME GRAPHICS LLC (US) 2005-08-18 US claimed
WO-2005030492-A1 BIGUANIDE BLEACHING AGENT FOR A THERMAL-IMAGING RECEPTOR ELEMENT KODAK POLYCHROME GRAPHICS LLC (US) 2005-04-07 WO claimed
US-11759441-B2 Biguanide compositions and methods of treating metabolic disorders ANJI PHARMACEUTICALS INC. (US) 2023-09-19 US disclosed
US-11759441-B2 Biguanide compositions and methods of treating metabolic disorders ANJI PHARMACEUTICALS INC. (US) 2023-09-19 US disclosed
EP-0225852-A2 Processing holograms ILFORD Limited (GB) 1987-06-16 EP disclosed
EP-0225853-A2 Holograms ILFORD Limited (GB) 1987-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11759441-B2 Biguanide compositions and methods of treating metabolic disorders SLC5A2, SLC5A1, GPR119 SPHK1 1998/4885EPHX1 2097/4885SPHK2 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.