SCHEMBL7861734

SCHEMBL7861734

N#Cc1ccc(F)c(F)c1C#N

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.43
CYP11B2 P19099 12/20 0.36
CYP11B1 P15538 11/20 0.36
BCAT1 P54687 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
NOTUM Q6P988 1/20 0.32
EGLN2 Q96KS0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396882 0.85 TRPV4 (0.41) TRPV4CYP11B2CYP11B1ESR1ESR2
SCHEMBL15442788 0.83 TRPV4 (0.45) TRPV4CYP11B2CYP11B1ESR1ESR2
SCHEMBL186689 0.82 TRPV4 (0.42) TRPV4BCAT1ESR1ESR2NOTUM
SCHEMBL9490088 0.81 TRPV4 (0.43) TRPV4CYP11B2CYP11B1BCAT1ESR1
SCHEMBL365967 0.80 TRPV4 (0.46) TRPV4CYP11B2CYP11B1BCAT1ESR1
SCHEMBL8811100 0.77 ESR1 (0.42) TRPV4ESR1ESR2
SCHEMBL7869818 0.77 CYP11B2 (0.41) TRPV4CYP11B2CYP11B1ESR1ESR2
SCHEMBL8623053 0.77 APP (0.41) CYP11B2CYP11B1
SCHEMBL31399295 0.76 TSHR (0.39) TRPV4
SCHEMBL152358 0.76 TSHR (0.39) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110752405-A Dendritic crystal inhibitor for negative electrode of lithium metal battery 南京航空航天大学 2020-02-04 CN claimed
CN-121865823-A Preparation method of pure iodine wide-bandgap perovskite solar cell based on difluoro phthalonitrile passivation 南开大学 2026-04-14 CN disclosed
CN-121865823-A Preparation method of pure iodine wide-bandgap perovskite solar cell based on difluoro phthalonitrile passivation 南开大学 2026-04-14 CN disclosed
US-12213375-B2 Photoelectric conversion film, photoelectric conversion element and electronic device SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2025-01-28 US disclosed
CN-112510154-B Photoelectric conversion film and electronic device 索尼半导体解决方案公司 2024-12-20 CN disclosed
CN-112510153-B Photoelectric conversion film and electronic device 索尼半导体解决方案公司 2024-11-15 CN disclosed
CN-112531120-B Photoelectric conversion film, photoelectric conversion element, and electronic device 索尼半导体解决方案公司 2024-10-22 CN disclosed
CN-112531121-B Photoelectric conversion film and electronic device 索尼半导体解决方案公司 2024-10-22 CN disclosed
CN-111029464-B Photoelectric conversion film, photoelectric conversion element, and electronic device 索尼半导体解决方案公司 2024-03-19 CN disclosed
US-20230329082-A1 PHOTOELECTRIC CONVERSION FILM, PHOTOELECTRIC CONVERSION ELEMENT AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2023-10-12 US disclosed
CN-103665920-B For high transmission green dye and the synthetic method thereof of liquid-crystal display LG DISPLAY CO., LTD. (KR) 2015-07-29 CN disclosed
CN-103665920-A High transmissional green dye for LCD and synthetic method thereof LG DISPLAY CO LTD 2014-03-26 CN disclosed
CN-102272235-A Method for preparing nanodispersions of fluorinated phthalocyanine pigments 2011-12-07 CN disclosed
CN-102227655-A Color filter element with improved colorant dispersion GLOBAL OLED TECHNOLOGY LLC 2011-10-26 CN disclosed
CN-102197096-A Fluorinated bis-(phthalocyanylaluminoxy)silyl pigments GLOBAL OLED TECHNOLOGY LLC 2011-09-21 CN disclosed
CN-1680380-B Method for production of halogen-containing phthalocyanine compound NIPPON CATALYTIC CHEM IND 2010-06-23 CN disclosed
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
JP-2000327652-A PHTHALONITRILE DERIVATIVE AND ITS PRODUCTION NIPPON SHOKUBAI CO LTD 2000-11-28 JP disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12213375-B2 Photoelectric conversion film, photoelectric conversion element and electronic device ETFA, TRRAP, TEAD4 TRPV4 1865/4885CYP11B2 2278/4885CYP11B1 2657/4885
US-20230329082-A1 PHOTOELECTRIC CONVERSION FILM, PHOTOELECTRIC CONVERSION ELEMENT AND ELECTRONIC DEVICE ETFA, TRRAP, TEAD4 TRPV4 1865/4885CYP11B2 2278/4885CYP11B1 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.